CUSIP No. 413197104
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Page 2 of 12 Pages
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1
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NAMES OF REPORTING PERSONS
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venBio Global Strategic Fund II, L.P.
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|||
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||||
2
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CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
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(a)☐
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|||
(b)☐
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3
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SEC USE ONLY
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||||
4
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CITIZENSHIP OR PLACE OF ORGANIZATION
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Cayman Islands
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NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
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5
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SOLE VOTING POWER
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0
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|||
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||||
6
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SHARED VOTING POWER
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3,504,624
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|||
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||||
7
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SOLE DISPOSITIVE POWER
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0
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|||
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||||
8
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SHARED DISPOSITIVE POWER
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||
3,504,624
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|||
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||||
9
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AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
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3,504,624
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|||
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||||
10
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CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
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☐
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|||
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||||
11
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PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
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6.2%
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|||
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||||
12
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TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
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PN
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CUSIP No. 413197104
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Page 3 of 12 Pages
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1
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NAMES OF REPORTING PERSONS
|
|
|
||
venBio Global Strategic GP II, L.P.
|
|
|
|||
|
|
||||
2
|
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
|
|
|
||
(a)☐
|
|
|
|||
(b)☐
|
|
|
|||
3
|
SEC USE ONLY
|
|
|
||
|
|
|
|||
|
|
||||
4
|
CITIZENSHIP OR PLACE OF ORGANIZATION
|
|
|
||
Cayman Islands
|
|
|
|||
|
|
||||
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
|
5
|
SOLE VOTING POWER
|
|
|
|
0
|
|
|
|||
|
|
||||
6
|
SHARED VOTING POWER
|
|
|
||
3,504,624
|
|
|
|||
|
|
||||
7
|
SOLE DISPOSITIVE POWER
|
|
|
||
0
|
|
|
|||
|
|
||||
8
|
SHARED DISPOSITIVE POWER
|
|
|
||
3,504,624
|
|
|
|||
|
|
||||
9
|
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
|
|
|
||
3,504,624
|
|
|
|||
|
|
||||
10
|
CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
|
|
|
||
☐
|
|
|
|||
|
|
||||
11
|
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
|
|
|
||
6.2%
|
|
|
|||
|
|
||||
12
|
TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
|
|
|
||
PN
|
|
|
|||
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CUSIP No. 413197104
|
|
Page 4 of 12 Pages
|
1
|
NAMES OF REPORTING PERSONS
|
|
|
||
venBio Global Strategic GP II, Ltd.
|
|
|
|||
|
|
||||
2
|
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
|
|
|
||
(a)☐
|
|
|
|||
(b)☐
|
|
|
|||
3
|
SEC USE ONLY
|
|
|
||
|
|
|
|||
|
|
||||
4
|
CITIZENSHIP OR PLACE OF ORGANIZATION
|
|
|
||
Cayman Islands
|
|
|
|||
|
|
||||
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
|
5
|
SOLE VOTING POWER
|
|
|
|
0
|
|
|
|||
|
|
||||
6
|
SHARED VOTING POWER
|
|
|
||
3,504,624
|
|
|
|||
|
|
||||
7
|
SOLE DISPOSITIVE POWER
|
|
|
||
0
|
|
|
|||
|
|
||||
8
|
SHARED DISPOSITIVE POWER
|
|
|
||
3,504,624
|
|
|
|||
|
|
||||
9
|
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
|
|
|
||
3,504,624
|
|
|
|||
|
|
||||
10
|
CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
|
|
|
||
☐
|
|
|
|||
|
|
||||
11
|
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
|
|
|
||
6.2%
|
|
|
|||
|
|
||||
12
|
TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
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||
CO
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CUSIP No. 413197104
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Page 5 of 12 Pages
|
1
|
NAMES OF REPORTING PERSONS
|
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|
||
Robert Adelman
|
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|||
|
|
||||
2
|
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
|
|
|
||
(a)☐
|
|
|
|||
(b)☐
|
|
|
|||
3
|
SEC USE ONLY
|
|
|
||
|
|
|
|||
|
|
||||
4
|
CITIZENSHIP OR PLACE OF ORGANIZATION
|
|
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||
United States
|
|
|
|||
|
|
||||
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
|
5
|
SOLE VOTING POWER
|
|
|
|
0
|
|
|
|||
|
|
||||
6
|
SHARED VOTING POWER
|
|
|
||
3,504,624
|
|
|
|||
|
|
||||
7
|
SOLE DISPOSITIVE POWER
|
|
|
||
0
|
|
|
|||
|
|
||||
8
|
SHARED DISPOSITIVE POWER
|
|
|
||
3,504,624
|
|
|
|||
|
|
||||
9
|
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
|
|
|
||
3,504,624
|
|
|
|||
|
|
||||
10
|
CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
|
|
|
||
☐
|
|
|
|||
|
|
||||
11
|
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
|
|
|
||
6.2%
|
|
|
|||
|
|
||||
12
|
TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
|
|
|
||
IN
|
|
|
|||
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CUSIP No. 413197104
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Page 6 of 12 Pages
|
1
|
NAMES OF REPORTING PERSONS
|
|
|
||
Corey Goodman
|
|
|
|||
|
|
||||
2
|
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
|
|
|
||
(a)☐
|
|
|
|||
(b)☐
|
|
|
|||
3
|
SEC USE ONLY
|
|
|
||
|
|
|
|||
|
|
||||
4
|
CITIZENSHIP OR PLACE OF ORGANIZATION
|
|
|
||
United States
|
|
|
|||
|
|
||||
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
|
5
|
SOLE VOTING POWER
|
|
|
|
0
|
|
|
|||
|
|
||||
6
|
SHARED VOTING POWER
|
|
|
||
3,504,624
|
|
|
|||
|
|
||||
7
|
SOLE DISPOSITIVE POWER
|
|
|
||
0
|
|
|
|||
|
|
||||
8
|
SHARED DISPOSITIVE POWER
|
|
|
||
3,504,624
|
|
|
|||
|
|
||||
9
|
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
|
|
|
||
3,504,624
|
|
|
|||
|
|
||||
10
|
CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
|
|
|
||
☐
|
|
|
|||
|
|
||||
11
|
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
|
|
|
||
6.2%
|
|
|
|||
|
|
||||
12
|
TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
|
|
|
||
IN
|
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|||
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CUSIP No. 413197104
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Page 7 of 12 Pages
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Item 1(a).
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Name of Issuer
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Item 1(b).
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Address of Issuer’s Principal Executive Offices
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Item 2(a).
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Names of Persons Filing
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i)
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venBio Global Strategic Fund II, L.P. (“Fund II”);
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ii)
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venBio Global Strategic GP II, L.P. (“General Partner II”);
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iii)
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venBio Global Strategic GP II, Ltd. (“GP Ltd. II”);
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iv)
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Robert Adelman (“Mr. Adelman”); and
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v)
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Corey Goodman (“Mr. Goodman”).
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Item 2(b).
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Address of Principal Business Office or, if None, Residence
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Item 2(c).
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Citizenship
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Item 2(d).
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Title of Class of Securities
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Item 2(e).
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CUSIP Number
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Item 3.
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If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
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Item 4.
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Ownership
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Item 4(a)
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Amount Beneficially Owned
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CUSIP No. 413197104
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Page 8 of 12 Pages
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Item 4(b)
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Percent of Class
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(c)
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Number of shares as to which such person has:
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(i)
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sole power to vote or to direct the vote: See Line 5 of cover sheets.
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(ii)
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shared power to vote or to direct the vote: See Line 6 of cover sheets.
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(iii)
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sole power to dispose or to direct the disposition of: See Line 7 of cover sheets.
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(iv)
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shared power to dispose or to direct the disposition of: See Line 8 of cover sheets.
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Item 5.
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Ownership of Five Percent or Less of a Class
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Item 6.
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Ownership of More than Five Percent on Behalf of Another Person
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Item 7.
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Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person
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Item 8.
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Identification and Classification of Members of the Group
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Item 9.
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Notice of Dissolution of Group
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Item 10.
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Certification
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CUSIP No. 413197104
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Page 9 of 12 Pages
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Ex.
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Page No.
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1
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Joint Filing Agreement
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11
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2
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Power of Attorney regarding filings under the Securities Exchange Act of 1934, as amended.
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12
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CUSIP No. 413197104
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Page 10 of 12 Pages
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VENBIO GLOBAL STRATEGIC FUND II, L.P.
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||||||
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|||||
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By:
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VENBIO GLOBAL STRATEGIC GP II, L.P.
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|
|||||
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General Partner
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|||||
|
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|||||
By:
|
venBio Global Strategic GP II, Ltd.
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||||||
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General Partner
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|||||
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By:
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*
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|||||
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Director
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|||||
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|||||
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VENBIO GLOBAL STRATEGIC GP II, L.P.
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||||||
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|||||
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By:
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VENBIO GLOBAL STRATEGIC GP II, LTD.
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|||||
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General Partner
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|||||
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|||||
By:
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*
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||||||
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Director
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|||||
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|||||
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VENBIO GLOBAL STRATEGIC GP II, LTD.
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||||||
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By:
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*
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||||||
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Director
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|||||
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*
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||||||
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Robert Adelman
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||||||
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*
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||||||
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Corey Goodman
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||||||
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||||||
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*By:
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/s/ David Pezeshki
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||||||
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David Pezeshki
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|||||
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As attorney-in-fact
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|||||
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CUSIP No. 413197104
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Page 11 of 12 Pages
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VENBIO GLOBAL STRATEGIC FUND II, L.P.
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||||||
|
|
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|
|||||
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By:
|
VENBIO GLOBAL STRATEGIC GP II, L.P.
|
|
|||||
|
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General Partner
|
|
|||||
|
|
|
|
|||||
By:
|
venBio Global Strategic GP II, Ltd.
|
|
||||||
|
|
General Partner
|
|
|||||
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By:
|
*
|
|
|||||
|
|
Director
|
|
|||||
|
|
|
|
|||||
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VENBIO GLOBAL STRATEGIC GP II, L.P.
|
|
||||||
|
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|
|||||
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By:
|
VENBIO GLOBAL STRATEGIC GP II, LTD.
|
|
|||||
|
|
General Partner
|
|
|||||
|
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|
|||||
By:
|
*
|
|
||||||
|
|
Director
|
|
|||||
|
|
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|
|||||
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VENBIO GLOBAL STRATEGIC GP II, LTD.
|
|
||||||
|
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|
|||||
By:
|
*
|
|
||||||
|
|
Director
|
|
|||||
|
*
|
|
||||||
|
Robert Adelman
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||||||
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*
|
|
||||||
|
Corey Goodman
|
|
||||||
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|
||||||
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|
|||||
*By:
|
/s/ David Pezeshki
|
|
||||||
|
|
David Pezeshki
|
|
|||||
|
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As attorney-in-fact
|
|
|||||
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CUSIP No. 413197104
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Page 12 of 12 Pages
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/s/ Robert Adelman
|
|
Robert Adelman
|
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/s/ Corey Goodman
|
|
Corey Goodman
|